Where is Klinefelter’s syndrome location?

It occurs as a random error during cell division early in fetal development. As a result, some of the body’s cells have the usual one X chromosome and one Y chromosome (46,XY), and other cells have an extra copy of the X chromosome (47,XXY).

Where is Klinefelter syndrome most common?

It is estimated that 1 in every 500 to 1,000 newborn males has an extra X chromosome, making Klinefelter syndrome one of the most common chromosomal disorders seen among newborns. Variants of Klinefelter syndrome (such as 48,XXXY, 49,XXXXY) are much rarer, occurring in 1 in 50,000 to 1 in 85,000 or fewer newborns.

CAN XXY have babies?

It is possible that an XXY male could get a woman pregnant naturally. Although sperm are found in more than 50% of men with KS³, low sperm production could make conception very difficult.

Does Klinefelter syndrome run in families?

Klinefelter syndrome isn’t passed down through families like some genetic diseases. Instead, it happens randomly from an error in cell division when a parent’s reproductive cells are being formed.

What is the survival rate of Klinefelter syndrome?

We found that Klinefelter syndrome was associated with a significant increase in mortality risk of 40% (hazard ratio, 1.40; 95% confidence interval, 1.13-1.74), corresponding to a significantly reduced median survival of 2.1 yr.

What is the life expectancy of someone with Klinefelter syndrome?

According to research, Klinefelter syndrome can shorten your life expectancy up to two years. However, you can still live a long, full life with this condition.

What does a person with Klinefelter syndrome look like?

Longer legs, shorter torso and broader hips compared with other boys. Absent, delayed or incomplete puberty. After puberty, less muscle and less facial and body hair compared with other teens. Small, firm testicles.

Is Klinefelter syndrome a disability?

If you or your dependent(s) are diagnosed with Klinefelter Syndrome and experience any of these symptoms, you may be eligible for disability benefits from the U.S. Social Security Administration.

How do they fix Klinefelter syndrome?

Treatment

1. Testosterone replacement therapy.
2. Breast tissue removal.
3. Speech and physical therapy.
4. Educational evaluation and support.
5. Fertility treatment.
6. Psychological counseling.

Should I be worried about Klinefelter syndrome?

If you’re worried about your son’s emotional or physical development, talk to your doctor. Occasionally, symptoms like these can be linked to a condition called Klinefelter syndrome.

Are XXY males infertile?

Between 95% and 99% of XXY men are infertile because they do not produce enough sperm to fertilize an egg naturally. But, sperm are found in more than 50% of men with KS.

What is the gender of XXY?

A person’s physical gender (whether they have male or female sex organs) is determined by the sex chromosomes: females have two X chromosomes, or XX; most males have one X chromosome and one Y chromosome, or XY. Males with Klinefelter syndrome are born with cells that have an extra X chromosome, or XXY.

Which parent is responsible for Klinefelter’s syndrome?

The mother is responsible for passing on one X chromosome to her child and the father may provide another X chromosome for a daughter or a Y chromosome for a son. A boy born with Klinefelter syndrome has an extra X chromosome that is believed to be caused by a random error.

Are there any support groups for Klinefelter syndrome?

The American Association for Klinefelter Syndrome Information and Support (AAKSIS) is a national volunteer association with the mission of education, support, research, and understanding of 47 XXY and its variants, collectively known as Klinefelter syndrome.